I-BET 151 hydrochloride

I-BET 151 hydrochloride (订货以CAS编码或英文名称为准)

I-BET 151 dihydrochloride is a bET bromodomain inhibitor that prevents BET from recruiting to chromatin. I-BET 151 induces MLL-fusion leukemia cell line apoptosis and G0 / G1 cell cycle arrest in vitro, and reduces BCL2 expression in NOMO1 cells.
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编号:MED11776
CAS号:1883545-47-8
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中文名称: I-BET151Dihydrochloride
英文名称: I-BET 151 hydrochloride
CAS号: 1883545-47-8
I-BET 151 dihydrochloride is a bET bromodomain inhibitor that prevents BET from recruiting to chromatin. I-BET 151 induces MLL-fusion leukemia cell line apoptosis and G0 / G1 cell cycle arrest in vitro, and reduces BCL2 expression in NOMO1 cells. I-BET 151 improves the survival rate of two kinds of MLL fusion leukemia mice, and enhances the differentiation of human iPSCs into megakaryocytes.
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