HE-3235

HE-3235 (订货以CAS编码或英文名称为准)

Apoptone, also known as HE3235, is an orally bioavailable adrenal steroid analogue with potential antineoplastic activity.
MedBio提供的所有产品仅用于科研等非医疗用途,非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。如您需要产品COA等资料,可至下方“质量控制”中下载
编号:MED12284
CAS号:183387-50-0
申请试用
货号 品牌 规格 纯度/含量 标准价 优惠价 库存货期 数量 购买
MED12284-25mg MedBio 25mg ≥98% ¥9100.00 登录后可见
MED12284-5mg MedBio 5mg ≥98% ¥2350.00 登录后可见
MED12284-10mg MedBio 10mg ≥98% ¥4145.00 登录后可见
中文名称: (3R,5S,8R,9S,10S,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
英文名称: HE-3235
CAS号: 183387-50-0
Apoptone, also known as HE3235, is an orally bioavailable adrenal steroid analogue with potential antineoplastic activity. Androstane steroid HE3235 appears to bind the androgen receptor (AR), down-regulating anti-apoptotic genes, such as Bcl-2, while increasing the expression of pro-apoptotic genes, such as caspases. In vitro and in vivo studies indicate that this agent inhibits androstenediol-dependent LNCaP cell tumor growth. In addition, HE3235 may potentiate chemotherapeutic agents by down-regulating ABCG2, the gene encoding the multi-drug resistant (MDR) protein MDR2.
搜索质检报告(COA)
相关产品