Cy3-UTP 抑制剂 BMPO Leukotriene D4 荧光染料 DMAPP 定制合成
AZD-8055中文别名:5-[2,4-双[(3S)-3-甲基-4-吗啉]吡啶并[2,3-d]嘧啶-7-基]-2-甲氧基苯甲醇 ;[5-[2,4-二((3S)-3-甲基吗啉-4-基)吡啶并[2,3-d]嘧啶-7-基]-2-甲氧基苯基]甲醇
1、AZD-8055用途: AZD-8055 是一种ATP竞争性的 mTOR 抑制剂,IC50 为 0.8 nM。AZD-8055 抑制 mTORC1 和 mTORC2。
2、AZD-8055物理化学性质:
3、AZD-8055英文别名:
4、AZD-8055参考文献:
[1]. Chresta CM, et al. AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. Cancer Res, 2010, 70(1), 288-298.
[2]. You W, et al. Inhibition of mammalian target of rapamycin attenuates early brain injury through modulating microglial polarization after experimental subarachnoid hemorrhage in rats. J Neurol Sci. 2016 Aug 15;367:224-31.
[3]. Kawata T, et al. Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia. Cancer Sci. 2017 Oct 27.
MedBio客服1
MedBio客服2
MedBio客服3
MedBio客服4
MedBio客服5
MedBio客服6
400-186-1816