Cy3-UTP 抑制剂 BMPO Leukotriene D4 荧光染料 DMAPP 定制合成
1、chymostatin物理参数:
常用名
胰凝乳蛋白酶抑制剂
英文名
chymostatin
CAS号
9076-44-2
分子量
607.701
密度
1.3±0.1 g/cm3
沸点
无资料
分子式
C31H41N7O6
熔点
276-278℃
闪点
2、chymostatin物理化学性质:
-20°C密闭,避光,通风干燥处
Biochem/physiol Actions Chymostatin is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, B, H, and L. It weakly inhibits human leucocyte elastase. It is effective at a final concentration of 100 to 200 μg/ml (10 to 100 μM). Chymostatin is often included in protease inhibitor cocktails used with plant extracts.
Other Notes A mixture of A (major), B and C components. A: X=Leu; B: X=Val; C: X=Ile
chymostatin A MW = 607.7
chymostatin B MW = 593.7
chymostatin C MW = 607.7
Preparation Note Solubility testing in glacial acetic acid at 10 mg/ml yields a clear solution, which is usually colorless, but can be yellow in appearance. It is reportedly also soluble in DMSO; only slightly soluble in water and short-chain alcohols; insoluble in ethyl acetate, butyl acetate, ether, hexane, and petroleum ether. Stock solutions ( 10 mM ) can be prepared in DMSO and are stable for months at -20 °C . Stock solutions can also be made in 0.1 M HCl. Dilute solutions (10-100 μM) are only stable for several hours, due to oxidation of the terminal aldehyde.
计算化学数据:
1、 疏水参数计算参考值(XlogP):未确定
2、 氢键供体数量:21
3、 氢键受体数量:27
4、 可旋转化学键数量:44
5、 拓扑分子极性表面积(TPSA):612
6、 重原子数量:131
7、 表面电荷:0
8、 复杂度:3010
9、 同位素原子数量:0
10、 确定原子立构中心数量:13
11、 不确定原子立构中心数量:3
12、 确定化学键立构中心数量:0
13、 不确定化学键立构中心数量:0
14、 共价键单元数量:1
3、chymostatin同类产品列表:
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED18563
Calpain Inhibitor XII
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1009734-33-1
25mg
MED18425
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865466-24-6
50mg
MED18559
UCF 101
313649-08-0
MED18504
CA-074 Me
147859-80-1
10mM (in 1mL DMSO)
MED18485
ARP 100
704888-90-4
10mg
MED18439
LY2811376
1194044-20-6
MED18495
BC 11 hydrobromide
443776-49-6
MED18481
NVP DPP 728 dihydrochloride
247016-69-9
MED18396
Leupeptin, Microbial
103476-89-7
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